Scientific Program
This conference was held virtually, over the course of ten weeks in late 2021. It comprised a total of six 1-1.5 hour meetings. Each meeting started with an invited Keynote lecture, followed by a break where videos of our sponsors were shown, and then two to four free paper presentations.
Best Paper Award
After each session a team of experts selected the best paper of this session and the winner was announced at the end of the discussions after the last paper.. This Award carriesd a prize money of 100 € was funded by donations from patients (originally targeted to support travel expenses of young researchers).
Sessions of the virtual International Dupuytren Symposium 2021
Session 1: Wednesday 22nd September, Time: 19:00 UTC (20:00 BST)
Basic Science, Epidemiology, Pathology, Genetics
Keynote: Biomarkers and the International Dupuytren Databank
Dr. Charles Eaton, Dupuytren Research Group, USA
video presentation and discussion
+ additional papers
1. The association of antihypertensive medication with Dupuytren disease severity
S.A. Riesmeijer, Groningen, The Netherlands – Awarded Best Paper
video presentation and discussion
2. A meta-analysis reveals new genetic loci associated with Dupuytren disease
S.A. Riesmeijer, Groningen, The Netherlands
video presentation and discussion
3. Human Type I Protein Arginine Methyltransferases Are Key Regulators of Human Fibrosis Through PLA2G2A
N. Yang, Oxford, UK
video presentation and discussion
4. New synthesis of homotrimeric collagen (I), matrix metalloproteinase-3 and TIMP2 in Dupuytren’s disease tissue
E. Laird, Liverpool, UK
video presentation and discussion
Session 2: Wednesday 6th October, Time: 19:00 UTC (20:00 BST)
Minimally invasive procedures
Keynote: Randomised controlled trials in Dupuytren Disease
Dr Joakim Strömberg, Sahlgrenska University Hospital, Sweden
video presentation and discussion
Special Instructional Lecture: How I do it – difficult PIPJ contractures treated with PNF or collagenase
Dr. Gary Pess, New Jersey, USA
video presentation and discussion
+ additional papers
1. Relationship between Pre-treatment Contracture Severity and The Effectiveness of Collagenase in Dupuytren’s Contracture
I. Motoroko, Victoria, Australia
video incl. discussion
2. Limited Fasciectomy versus Collagenase Clostridium Histolyticum for Dupuytren Contracture: A Propensity Score Matched Study of Single Digit Treatment with Minimum Five-Year Follow-Up
J. Gruber, Boston, MA, USA – Awarded Best Paper
video incl. discussion
Session 3: Wednesday 20th October, Time: 19:00 UTC (20:00 BST)
Classical Surgical Approaches
Keynote: Classic Surgical Approaches in DD, including PIPJ Management
Prof. Paul Werker, UMCG, Groningen, The Netherlands
video presentation and discussion
+ additional papers
1. Dupuytren’s disease: Prevalence, incidence, and lifetime risk of surgical intervention
C. Broekstra, Groningen, The Netherlands – Awarded Best Paper.
video presentation and discussion
2. Serious adverse events and risk of re-operation after Dupuytren’s disease surgery: a longitudinal population-based cohort study using Hospital Episode Statistics for England
O, Alser, Oxford, UK
video presentation and discussion
3. Skin Graft Review in Dermofasciectomy for Dupuytren’s Contracture within 48 Hours: Challenging Historical Practice
S.A. Ansari, Lancashire, UK
video presentation and discussion
4. Utility of Routine Pathologic Examination for Limited Fasciectomy for Dupuytren Contracture
D. Liu, Boston, MA, USA
video presentation and discussion
Session 4: Wednesday 3rd November, Time: 20:00 UTC (20:00 GMT)
Radiotherapy
Keynote: Radiotherapy for Dupuytren Disease
Dr. Richard Shaffer, The Dupuytren’s Practise, London, UK
video presentation and discussion
+ additional papers
1. A Randomized trial of Radiotherapy for Dupuytren’s Disease – DEPART
J. Martin, Newcastle, Australia
video_presentation and discussion
2. Radiotherapy for patients with Ledderhose disease: long-term efficacy, side effects and patient-rated outcome
A. de Haan, Groningen, The Netherlands
video presentation
3. Radiotherapy in patients with painful Ledderhose disease: a randomised, multicenter, prospective, double-blind phase III trial.
A. de Haan, Groningen, The Netherlands – Awarded Best Paper.
video presentation and discussion
Session 5: Wednesday 17th November, Time: 20:00 UTC (20:00 GMT)
Measurement and Patient Experience
Keynote: Overview of PROMs in Dupuytren Disease
Mr. Jeremy Rodrigues, NDORMS, Oxford University, UK
video presentation and discussion
+ additional papers
1. Validation of a Spanish version of Unité Rhumatologique des Affections de la Main (URAM) scale
R. Sanjuan-Cervero, Denia, Spain
video presentation and discussion
2. Can a decrease in patient-perceived hand function measured with the URAM scale predict surgical intervention for DD?
B. van den Berge, Groningen, The Netherlands – Awarded Best Paper..
video presentation and discussion
3. Patient Preferences for Limited Fasciectomy Versus Collagenase Treatment for Dupuytren Contractures
B. Earp, Boston, MA, USA
video presentation and discussion
Session 6: Wednesday 1st December, Time: 20:00 UTC (20:00 GMT)
Experimental Treatments
Keynote: Re-purposing anti-TNF for Dupuytren’s Disease
Prof. Jagdeep Nanchahal, Kennedy Institute of Rheumatology, Oxford, UK
video presentation and discussion
+ additional papers
1. Does injectable corticosteroid augment the durability of collagenase treatment for Dupuytren’s disease?
R. Phan, Victoria, Australia
video presentation (no discussion because speaker was not available)
2. Successful conservative contracture treatment in Dupuytren’s disease with a dynamic extension orthosis
W. Lenze, Bielefeld, Germany. – Awarded Best Paper.
video presentation and discussion. Closing of the symposium.
The whole program as PDF: Program_Dupuytren_Symposium_2021
We very much appreciate the support by our sponsors of the International Dupuytren Symposium 2021: sponsors