A short overview with comments and statements recorded during this conference:
https://youtu.be/fefyxEUWEKU

Please find below the Scientific Program for the International Dupuytren Conference on May 16th and 17th 2025 at the Nhow Brussels Bloom Hotel.

Scientific Program

Pro Q Kine approved: ID612158 (31 points Manual Therapy – 24 points National Symposium)

Day 1: Friday, May 16
Presidential welcome
09:00 Welcome – Bernard Lefebvre, Rozemie Zenner, Ilse Degreef video
09:10 Opening Address – Wolfgang Wach video

Session 1: Pathophysiology – Dominic Furniss, Charles Eaton
09:25 Pathogenesis of Dupuytren’s Disease – Charles Eaton video
09:40 Genetics of Dupuytren disease – Dominic Furniss video
09:55 Associations of demographic, lifestyle and clinical factors with the presence of Dupuytren’s disease: results from the Lifelines Cohort Study – Michel Noordman video
10:02 Metabolic Determinants in Dupuytren’s Disease: A Mendelian Randomisation Analysis -Max Butler video
10:09 Polygenic risk score predicts recurrence, its severity, and retreatment for Dupuytren’s disease – Sophie Riesmeijer video
10:16 Investigating Genes of Interest in Dupuytren Disease – Ben Christensen video

Session 2: Cellular Biology – David O’Gorman, Ilse Degreef
11:08 Controversies in Cellular Events – David O’Gorman video
11:23 Biomechanics, epigenetics and fibrosis – Boris Hinz — no video recorded as requested by the author
11:38 The abnormal mechanotransduction response of Dupuytren’s fibroblasts from patients with the disease-associated MMP14 Single Nucleotide Polymorphism – Mira Pecheva video
11:45 The presence of microvascular structures in Dupuytren’s disease on ultrasound images: A case study – Leander Swinnen video

Session 3: Assessment & Therapeutic Management – Jagdeep Nanchahal, Donna Kennedy
13:45 Early Disease Treatment of Dupuytren’s – Jagdeep Nanchahal — no video recorded as requested by the author
14:00 Hand therapy in managing fibrosis, soft-tissue attenuation and scarring in the post-surgical hand. Why is the PIP joint such a jerk? – Donna Kennedy video
14:15 Splinting in Dupuytren – evidence based therapy? – Sonja Pelzmann video
14:30 Modern approach to the classification of Dupuytren’s disease – Andrey Zhigalo video
14:37 Sensitivity of the outcome measurements used for evaluating treatment effectiveness in Dupuytren´s disease – Teemu Karjalainen video
14:44 Agreement between photographic and goniometric measurements of Dupuytren’s contracture – a DISC substudy – Nick Johnson – no video recorded
14:51 Sensor-Controlled Patient Compliance with Postoperative Splinting after Dupuytren’s Surgery – Bram Van Hove video
14:58 Preoperative serial casting, stretching, and massage therapy will improve surgical outcomes in Dupuytren’s fasciectomy patients with severe proximal interphalangeal (PIP) joint contracture – Tahra Babiker-Moore video
15:05 The use of Virtual Reality during hand therapy after Dupuytren surgery – Tom Lattré video
15:12 Dynamic Low-force Finger Stretching in Dupuytren’s Patients by Use of an Orthosis; Post Product Development Case Studies – Lotte Lammers video

Session 4: Minimal invasive treatment of Dupuytren contracture – Gary Pess, Esther Vögelin
16:04 Comparative Studies of Treatments – Tim Davis video
16:19 Minimally Invasive Treatments – Gary Pess video
16:34 Ultrasound in Dupuytren Diagnosis and Treatment – Esther Vögelin video
17:04 Long-term assessment of collagenase treatment for Dupuytren’s contracture: A 10-year follow-up study – Vitale Cilli video
17:18 Comparison of contracture recurrence after fasciectomy, needle aponeurotomy or collagenase Clostridium histolyticum: A systematic review of prospective data with minimum 2-year follow-up – Mark Vitale video
17:25 Collagenase Clostridium histolyticum is an effective treatment of contracture recurrence after surgery: A retrospective multicenter series – Mark Vitale video
17:32 Re-Recurrence Rate Two Years after Fasciectomy vs Collagenase in Recurrent Contracture: Randomized Controlled Trial – Isam Atroshi — no video recorded as requested by the author
17:39 A case series of percutaneous sonography guided contracture release – Fabian Moungondo video

Day 2: Saturday, May 17
Session 5: Radioprotection & Radiotherapy in Hand Surgery – Jarad Martin, Anneke de Haan
08:30 Radioprotection in hand surgery – Hilde Bosmans video
09:30 Radiotherapy for Dupuytren’s and related conditions – Jarad Martin video
09:45 Radiotherapy in clinical practice – Anneke de Haan video
10:45 A Comparative Longitudinal Observational Cohort Study of Fractionated Superficial Radiotherapy Treatment of Dupuytren’s Disease – Henry Weatherburn video
10:52 Clinical Implementation of 3D-Printed compensator for Dupuytren Electron Radiotherapy – David Roberge video
10:59 Radiotherapy for symptomatic knuckle pads/Garrod’s nodes: Report of a case series – Elisabeth Weiss video
11:06 Radiotherapy for Ledderhose disease: Results of the LedRad-study, a prospective multicentre randomised double-blind phase III trial – Anneke de Haan video
11:13 Evaluating the Safety and Efficacy of Adjuvant Radiation Therapy in combination with Contracture Release: A Prospective Study – Leslie Chang video

Session 6: Surgical treatment of Dupuytren contracture and related diseases – Jean-Paul Brutus, Bernard Lefebvre
11:35 WALANT in hand surgery: Technique and indication – Donald Lalonde (online)
11:50 WALANT in hand surgery for Dupuytren: Results and patients experience – Jean-Paul Brutus video
12:20 Presenting the International Dupuytren Award 2025 – Wolfgang Wach video
13:50 Surgical Treatment: Dermo-fasciectomy – Dominique Davidson video
14:05 Peyronie’s Disease: Diagnosis and Treatment – David Ralph video
14:20 Outcomes of limited fasciectomy, needle fasciotomy and collagenase in Dupuytren’s disease – a systematic review and meta-analysis of individual patient data – Bente van den Berge video
14:27 Progression of Dupuytren’s contracture: a secondary analysis of a randomized controlled trial comparing surgery, needle fasciotomy, and collagenase injection – Teemu Karjalainen video
14:34 The Likelihood of Further Dupuytren Disease Intervention After Initial Treatment – Rayan El Bachaoui video
14:41 The added value of skin grafting in surgery for Dupuytren’s contracture: an effective method for severe cases with a low recurrence rate – Francine Vos video
14:48 McCash’s old and not often used technique in severe Dupuytren’s disease – Bernard Lukas video

Session 7: Salvage in Dupuytren treatment: when all else fails – Jean Goubau, Rozemie Zenner
15:10 Salvage Procedures for Recurrent Dupuytren’s Disease – Jean Goubau video
15:25 Dupuytren’s Disease under the Microscope – Ilse Degreef video
15:40 Arthrolysis of PIP joint in Dupuytren’s contracture – Floor Van den Eynde video
15:47 Long-term results of the Malingue technique in the surgical treatment of Dupuytren’s disease – Alexandre Petit video
15:54 Middle phalangectomy with shortening fusion of the fifth finger in Dupuytren’s digital hooks – Alexandre Petit video
16:01 Proximo-Distal Interphalangeal Arthrodesis as a First-Line Treatment for Severe Contracture of the Fifth Finger: Key Insights and Pitfalls to Avoid – Caro Roten video

Session 8: Ethical Considerations and Patient Perspectives – Anna Schurer, Paul Werker
16:53 The Patient Pathway – Anna Schurer video
17:08 Shared Decision-Making in Dupuytren Disease within National Health Systems – Jonathan Hobby video
17:15 Philosophy of treatment surgery – Paul Werker video
17:30 Clinician-patient collaboration: assessment, outcome measures and shared decision making – Ruud Selles video
17:45 Patient Perspectives on Dupuytren’s Contracture Treatments: A Sentiment Analysis of Social Media Comments – Cameron Sabet video
17:52 An economic evaluation of radiotherapy for patients with symptomatic Ledderhose disease – Anneke de Haan video
17:59 Dupuytren’s disease in General Practitioner care – Paul Werker video
18:06 Silent Signals: From Hands to Heart – Ethical Imperatives in Dupuytren, Carpal Tunnel, and Amyloidosis – Arne Decramer video
18:28 Closing Words – Ilse Degreef video

E-Posters
Flexor tendon rupture in PNF – N. Debaenst poster
Proteomic comparison of clubfoot and Dupuytren disease – A. Eckhardt poster
Combined Use of Superficial X-ray Radiotherapy (SXRT) and Collagenase – J. Glees poster
Fractionated Superficial RT of Ledderhose – J. Glees poster
Flap reconstruction in a severe case of recurrent DD – M. Harryson poster
Analysis of microfasciectomy and traditional fasciectomy – H. Hutsebaut poster
3D in vitro model of Dupuytren´s disease – J. Knitlova poster
Thumb web release for hyperextended MCPJ using PNF – O. Mercury poster
Ultrasound for monitoring response to radiotherapy – N. Niranjan poster
Evaluation of CNT201: A Novel Recombinant Collagenase Injection – K. Suntae poster
Animal model for DD in normothymic rat paws – M. van Nuffel poster
Histological Changes in Dupuytren Contractures Treated with Tamoxifen – M. van Nuffel poster
Photograph-Based vs. Clinical Goniometry – L. Wattecamps poster
Linear accelerator or XRT for Dupuytren’s Disease or Ledderhose – H. Weatherburn poster
Surgical tactics for treatment of Dupuytren’s contracture – A. Zhigalo poster

Organizing Committee

Prof. Ilse Degreef, UZ Leuven, Belgium
supported by
Dr. Charles Eaton, Dupuytren Research Group, USA
Prof. Dominic Furniss, NDORMS, Oxford, UK
Prof. David O’Gorman, The University of Western Ontario, Canada
Anna Schurer, International Dupuytren Society
Prof. Paul Werker, UMC Groningen, The Netherland